Reduced left ventricular myocardial blood flow per unit mass in aortic stenosis.

Reduced left ventricular myocardial blood flow per unit mass in aortic stenosis.

Myocardial blood flow (MBF) per unit mass was measured in 10 patients (pts) with severe aortic stenosis (AS) and no significant aortic insufficiency, normal ejection fractions, and normal coronary arteriograms, using xenon-133 and a multiple crystal scintillation camera. MBF per unit mass was reduced in AS (53 +/- 13 mg/100g.min) in comparison to a group of seven normal control patients (69 +/-...

Low-flow aortic stenosis and preserved left ventricular ejection fraction.

Valvular aortic stenosis (AS) is the most frequent valvular disease in developed countries. Treatment decisions in AS are mainly based upon the symptomatic status of the patient and the severity of AS. Doppler echocardiography represents the standard tool for detecting and assessing the severity of the disease. Under the same denomination of severe AS [aortic valve area (AVA) < 1 cm(2)], severa...

Alterations of myocardial blood flow associated with experimental canine left ventricular hypertrophy secondary to valvular aortic stenosis.

Experimental renovascular hypertension or supravalvular aortic constriction results in left ventricular hypertrophy and impaired minimum coronary vascular resistance. However, these experimental models expose the coronary arteries to increased intra-arterial pressure, so that hypertensive vascular changes might be responsible for the impaired minimum coronary resistance. This study was performe...

Short-Term Regression of Left Ventricular Mass After Aortic Valve Replacement in Aortic Stenosis With Left Ventricular Concentric Hypertrophy

Left Ventricular Myocardial Blood Flow in MNultivessel Coronary Artery Disease

The relationship between resting left ventricular (LV) myocardial blood flow (MBF) and hemodynamic determinants of myocardial oxygen consumption was investigated in 15 patients with multivessel coronary artery disease (CAD) and in 10 patients with normal coronary arteriograms. MeanLV MBF.per unit mass of tissue was measured with a multicrystal scintillation camera from the regional clearance ra...